About Jay Reddy

Graduate student works in Dr. Reddy's lab,.

Our long-term interest is the cellular and molecular mechanisms underlying the development of human autoimmune diseases. Most healthy humans have a propensity to develop autoimmune diseases, as evidenced by the presence of autoreactive T cells or autoantibodies in their na¯ve periphery. T cells are educated in the thymus, where high-affinity TCR-bearing cells that interact with self-antigens are deleted by negative selection while T cells with low-affinity TCR to self-antigens are selected positively and exported to the periphery. In spite of the high frequency of self-reactive T cells in the naïve peripheral repertoires, autoimmune responses do not ensue spontaneously. How this tolerance is maintained is a fundamental question. We focus our investigations on the role of reactive oxygen species in the maintenance of T cell tolerance and autoimmunity.

Jay Reddy, MVSc., PhD

Photo of Jay Reddy sitting and posting

Office location
202 VBS

Phone
402-472-8541

Email
jayreddy@unl.edu

Fax
402-472-9690

 

Our graduate programs

Education

1985Bachelor of Veterinary Sciences (BVSc), University of Agricultural Sciences, Bangalore, India
1990Master of Veterinary Science (MVSc) in Veterinary Medicine, University of Agricultural Sciences, Bangalore, India
1998PhD in Porcine Immunology, Department of Pathobiology, University of Guelph, Ontario, Canada

Postdoctoral training

1998-2000Department of Molecular Immunology, Pasteur Institute, Paris, France
2000-2003Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital/Harvard Medical School, Boston, MA

Employment

University related
1986-1993Instructor, Department of Medicine, Veterinary College, University of Agricultural Sciences (UAS), Bangalore, India
2003-2006Instructor, Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital/Harvard University, Boston, MA
2007-PresentProfessor, School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE
Pharmaceutical industry
2006-2007Senior Research Investigator, Central Nervous System Therapeutic Department (multiple sclerosis drug discovery research), Sanofi-Aventis, Bridgewater, NJ

Editorial boards

2014-PresentAcademic Editor, PLOS ONE
Associate Editor, BMC Immunology
Editor, Immunology and Infection Section, Journal of Visualized Experiments

Professional organizations and memberships

2009-PresentAmerican Association of Immunologists
Redox Biology Center
Nebraska Center for Virology

Honors and awards

1980-1985National Loan Scholarship for Bachelor of Veterinary Sciences, Government of India
1985Graduate Fellowship for MVSc, Indian Council for Agricultural Research, Government of India (based on national-level competition)
1990Gold Medal for Master of Veterinary Sciences (MVSc), Bangalore, India
1994Graduate Scholarship, University of Guelph, Canada
1994-1998Canadian Commonwealth Scholarship for PhD, Government of Canada
1995Betty Goldhart Fellowship, University of Guelph, Canada
1996Milton Travel Scholarship, University of Guelph, Canada
1997Pfizer Research Excellence Award, University of Guelph, Canada
1998Pathobiology Graduate Student Excellence, University of Guelph, Canada
2001-2004Advanced postdoctoral fellowship award, National Multiple Sclerosis Society, New York
2002Travel Award, 2nd Annual Federation of the Clinical Immunological Society
2010Superior Academic Advising Award, College of Agricultural Sciences and Natural Resources, University of Nebraska-Lincoln, Lincoln, NE